First of all, you need to format your USB drive ready for adding the bootable image to it. Start the Disk Utility, in Applications->Utilities. Select the USB drive you've inserted and format it per the options shown below.
$ hdiutil convert -format UDRW -o Fedora-18-x86_64-Live-Desktop.img Fedora-18-x86_64-Live-Desktop.iso
$ diskutil list
/dev/disk0
#: TYPE NAME SIZE IDENTIFIER
0: GUID_partition_scheme *500.1 GB disk0
1: EFI 209.7 MB disk0s1
2: Apple_HFS Macintosh HD 499.2 GB disk0s2
3: Apple_Boot Recovery HD 650.0 MB disk0s3
/dev/disk1
#: TYPE NAME SIZE IDENTIFIER
0: Apple_partition_scheme *17.4 MB disk1
1: Apple_partition_map 32.3 KB disk1s1
2: Apple_HFS Flash Player 17.3 MB disk1s2
/dev/disk2
#: TYPE NAME SIZE IDENTIFIER
0: *2.0 GB disk2
/dev/disk0
#: TYPE NAME SIZE IDENTIFIER
0: GUID_partition_scheme *500.1 GB disk0
1: EFI 209.7 MB disk0s1
2: Apple_HFS Macintosh HD 499.2 GB disk0s2
3: Apple_Boot Recovery HD 650.0 MB disk0s3
/dev/disk1
#: TYPE NAME SIZE IDENTIFIER
0: Apple_partition_scheme *17.4 MB disk1
1: Apple_partition_map 32.3 KB disk1s1
2: Apple_HFS Flash Player 17.3 MB disk1s2
/dev/disk2
#: TYPE NAME SIZE IDENTIFIER
0: *2.0 GB disk2
$ dd if=./Fedora-18-x86_64-Live-Desktop.img of=/dev/rdisk2 bs=1m